Graduate Pharmacy Aptitude Test
Graduate Pharmacy Aptitude Test

GPAT Syllabus 2025: Check Subject-Wise GPAT Syllabus, Exam Pattern, Weightage

The syllabus for the GPAT exam is prescribed by the All India Council for Technical Education (AICTE). Aspiring candidates must thoroughly go through the GPAT 2025 exam syllabus in order to effectively prepare for the exam. 
GPAT Syllabus 2025

GPAT Syllabus 2025

GPAT Syllabus 2025: The The National Board of Examinations in Medical Sciences (NBEMS) will release the official notification for the GPAT 2025 examination on its official website. Aspiring candidates must thoroughly go through the GPAT exam syllabus to effectively prepare for the exam. 

Along with the syllabus, candidates must also carefully go through the GPAT exam pattern 2025 and marking scheme before beginning their exam preparation. The exam will contain various questions from subjects like physical chemistry, organic chemistry, pharmaceutics etc. There will be a total of 125 questions in the exam and the total marks are 500. The GPAT exam will be conducted in the Computer Based Test (CBT) mode.

Candidates need to strategically approach the GPAT exam preparation by keeping in mind the exam syllabus, marking scheme and exam pattern. Candidates should also refer to the previous year's questions papers and try to solve as many mock tests as possible to comprehensively prepare for the GPAT exam 2025.

GPAT Syllabus 2025: Subject-wise

The candidates need to have a clear understanding of the syllabus before they start preparing for the exam. Candidates can refer to the following subject-wise GPAT syllabus:

Subjects

Topics

Physical Chemistry

  1. Composition and physical states of matter
  2. Colligative Properties
  3. Thermodynamics
  4. Refractive Index
  5. Solutions
  6. Electrochemistry
  7. Ionic Equilibrium
  8. Kinetics

Physical Pharmacy 

  1. Matter, properties of matter
  2. Micromeritics and powder rheology
  3. Surface and Interfacial Phenomenon
  4. Viscosity and Rheology
  5. Dispersion Systems
  6. Complexation
  7. Buffer
  8. Solubility

Organic Chemistry

  1. General Principles
  2. Different classes of compounds
  3. Protection and deprotection of groups
  4. Aromaticity and chemistry of aromatic compounds
  5. Different aromatic classes of compounds
  6. Polycyclic aromatic hydrocarbons
  7. Carbonyl Chemistry
  8. Heterocyclic Chemistry
  9. Bridged rings 
  10. Kinetic & thermodynamic control 
  11. Stereochemistry
  12.  Carbohydrates 
  13. Amino acids & proteins 
  14. Pericyclic reactions 

Pharmaceutical Chemistry

1. Pharmaceutical Inorganic Chemistry 

  •  Pharmaceutical Impurities
  •  Monographs 
  •  Isotopes 
  •  Dentifrices, desensitizing agents, & anticaries agents 

2. Medicinal Chemistry 

  • Therapeutic classes of drugs 
  • Various classes of therapeutic agents 
  • Different classes of therapeutic drugs 
  • Different classes of therapeutic drugs 

Pharmaceutics

  1. Pharmacy Profession & Introduction to Pharmaceuticals 
  2. Introduction to dosage form 
  3. Sources of drug information 
  4. Allopathic dosage form 
  5. Crude extract 
  6. Allergenic extract 
  7. Biological products 
  8. Pharmaceutical Plant, location, layout 
  9. Dosage Form Necessities and Additives 
  10. Powders 
  11. Capsules 
  12. Tablets 
  13.  Parenterals - product requiring sterile packaging 
  14. Suspensions
  15. Emulsions 
  16. Suppositories
  17. Semisolids 
  18. Liquids(solutions, syrups, elixirs, spirits, aromatic water, liquid for external uses) 
  19. Pharmaceutical Aerosols 
  20. Ophthalmic preparations 
  21. Preformulations 
  22. Stability of formulated products 
  23. Prolonged Action Pharmaceuticals 
  24. Novel Drug delivery system 
  25. GMP and Validation 
  26. Packaging Materials 
  27. Cosmetics 
  28. Pilot plant scale-up techniques 

Pharmacology 

  1. General Pharmacology 
  2. Neurohumoral transmission in autonomic and central nervous system
  3. Pharmacology of peripheral nervous system 
  4. Pharmacology of central nervous System 
  5. Pharmacology of cardiovascular system 
  6. Drugs acting on urinary system 
  7. Drugs acting on Respiratory system 
  8. Pharmacology of Endocrine system 
  9. Chemotherapy 
  10. Autacoids and their Antagonists 
  11. Pharmacology of drug acting on the gastrointestinal tract
  12. Chronopharmacology
  13. Immunopharmacology 
  14. Vitamins & Minerals
  15. Principles of toxicology

Pharmacognosy

  1. Introductory Pharmacognosy 
  2. Classification of crude drugs 
  3. Factors influencing quality of crude drugs 
  4. Techniques in microscopy 
  5. Introduction to phytoconstituents 
  6. Principles of plant classification 
  7. Pharmaceutical aids 
  8. Animal products 
  9. Plant products
  10. Toxic drugs 
  11. Enzymes
  12. Natural pesticides and insecticides 
  13. Adulteration and evaluation of crude drugs 
  14. Quantitative microscopy 
  15. Biogenetic pathways 
  16. Carbohydrates & lipids 
  17. Tannins 
  18. Volatile oils 
  19. Resinous drugs 
  20. Glycosides
  21. Alkaloids 
  22. Extraction and Isolation Techniques 
  23. Phytopharmaceuticals 
  24. Quality control and Standardization of herbal drugs 25. Herbal formulations 
  25. Worldwide trade of crude drugs and volatile oils 
  26. Herbal cosmetics
  27. Traditional herbal drugs 
  28. Plants based industries and research institutes in India
  29. Patents
  30. Ayurvedic system of medicine 
  31. Homoeopathic system of medicine

Pharmaceutical Analysis 

  1. Importance of quality control in pharmacy 
  2. Acid-base titrations 
  3. Non-aqueous titrations
  4. Oxidation-reduction titrations
  5. Precipitation titrations 
  6. Complexometric titrations 
  7. Gravimetry 
  8. Extraction techniques 
  9. Potentiometry 
  10. Miscellaneous methods of analysis 
  11. Calibration 
  12. General principles of spectroscopy 
  13. Ultraviolet-visible Spectrometry 
  14. Spectrofluorimetry
  15. Flame photometry & atomic absorption spectrometry 16. Infrared spectrometry 
  16. Proton nuclear magnetic resonance spectrometry 
  17. Mass spectrometry 
  18. Polarography
  19. Nephelometry & Turbidimetry 
  20. Chromatography  
  21. Miscellaneous 

Biochemistry

  1. Cell 
  2. Carbohydrates 
  3. Proteins
  4. Lipids 
  5. Vitamins 
  6. Biological oxidations & reductions 
  7. Enzymes 
  8. Nucleic acids 
  9. Hereditary diseases

Biotechnology

  1. Plant Cell and Tissue Culture 
  2. Animal Cell Culture
  3. Fermentation Technology and Industrial Microbiology.
  4. Recombinant DNA Technology 
  5. Process and Applications
  6. Biotechnology Derived Products

Microbiology

  1. Introduction to Microbiology
  2. Microscopy and staining technique
  3. Biology of Microorganisms
  4. Fungi and Viruses
  5. Aseptic Technique
  6. Sterilization & Disinfection 
  7. Microbial spoilage 
  8. Vaccines & Sera 
  9. Microbial Assay 

Pathophysiology

  1. Basic principles of cell injury and adaptation 
  2. Basic mechanisms of inflammation and repair 
  3. Disorders of fluid, electrolyte and acid-base balance
  4. Disorders of homeostasis: white blood cells, lymphoid tissues, and red blood cells related diseases
  5. Immunopathology including amyloidosis 
  6. Infectious diseases 
  7. Neoplastic diseases 
  8. Pathophysiology of common diseases
  9. Laboratory tests for Liver function tests and kidney function tests

Biopharmaceutics and Pharmacokinetics

  1. Bio-pharmaceutics 
  2. Bio-availability & Bio-equivalence
  3. Bio-pharmaceutical statistics 

Clinical Pharmacy and Therapeutics

Basic concepts and general principles

Human Anatomy and Physiology

  1. Cell physiology 
  2. The Blood 
  3. Gastrointestinal tract 
  4. Respiratory System 
  5. Autonomic nervous system
  6. Sense organs 
  7. Skeletal System 
  8. Central Nervous system 
  9. Urinary System 
  10. Endocrine Glands 
  11. Reproductive System 
  12. Cardiovascular system 13. Lymphatic system

Pharmaceutical Engineering

  1. Fluid flow 
  2. Heat transfer 
  3. Evaporation
  4. Distillation 
  5. Drying
  6. Size reduction and size separation 
  7. Extraction 
  8. Mixing 
  9. Crystallisation 
  10. Filtration and Centrifugation 
  11. Dehumidification and humidity control 
  12. Refrigeration and air conditioning 
  13. Material of constructions 
  14. Automated process control systems
  15. Industrial hazards & safety precautions

Pharmaceutical Management

  1. Introduction to management 
  2. Planning and Forecasting 
  3. Organization 
  4. Research Management 
  5. Inventory Management 
  6. Communication 
  7. Marketing Research 
  8. Leadership and motivation 
  9. Human resource and development (HRD)
  10. GATT
  11. World trade organization (WTO) and trade-related intellectual property rights (TRIPS) 
  12. Standard institutions and regulatory authorities 

Pharmaceutical Jurisprudence

Basic Concepts like historical background, relevant acts and rules

Dispensing and Hospital Pharmacy

  1. Basic Concepts
  2. Compounding and dispensing of certain prescriptions
  3. Reading and counselling of prescriptions from the clinical practice

GPAT Exam Pattern 2025

The GPAT examination 2025 shall be a multiple choice questions test delivered using computers network (CBT) as per scheme prescribed below. 


Sections


No. of Questions


Maximum Marks


Pharmaceutical Chemistry and Allied Subjects


38


152


Pharmaceutics and Allied Subjects


38


152


Pharmacognosy and Allied Subjects


10


40


Pharmacology and Allied Subjects


28


112


Other Subjects


11


44


Total


125


500

GPAT 2025 Marking Scheme

Candidates can go through the GPAT marking scheme 2025 given in the table below. 

Response Marks
Correct response 4 marks 
Incorrect response 1 mark shall be deducted
Unattempted question Zero

Note - There shall be 25% negative marking for incorrect answers. No marks will be deducted for unattempted questions

GPAT Exam 2025 - Preparation Tips

Candidates are advised to keep in mind the following preparation tips in order to prepare well for the GPAT exam:

  • Go through the syllabus carefully: Candidates must ensure that before they begin preparing for the GPAT exam, they must thoroughly read the syllabus and understand what the exam is actually about.
  • Know the exam pattern and marking scheme well: Along with the syllabus, candidates should also have a clear understanding of the GPAT exam pattern and marking scheme. Since there is a provision for negative marking in the exam, candidates should consider this point while preparing for the exam.
  • Refer to the relevant books: Candidates are advised to create a concise booklist for the examination and then stick to it. This will help them stay focused during the preparation period.
  • Make your own notes: Instead of referring to the books again and again, candidates are advised to make their own notes. This will help them prepare more comprehensively for the GPAT exam.
  • Repeated Revision: Simply learning the concepts won’t be enough. Candidates need to repeatedly revise their concepts.
  • Consistency and Discipline is the key: Candidates should be consistent, patient and disciplined while preparing for the exam no matter how challenging the preparation period may be
  • Take care of your health: Along with studying well, it is also important for the candidates to take care of their health. This includes taking breaks from time to time, sleeping well and eating nutritious food.

Frequently Asked Questions (FAQs)

How many subjects do I have to prepare for the GPAT exam 2025?

For the GPAT 2025 exam, you need to prepare a total of 19 subjects. These subjects include Pharmacology, Pharmaceutical jurisprudence, organic chemistry, physical chemistry, Microbiology etc. Different subjects will have different weightage in the GPAT exam.

Will it be enough if I just refer to NCERTs for my GPAT 2025 exam preparation?

You need to go through the NCERTs in order to clear your basic concepts that are relevant for the GPAT exam. However, just referring to the NCERTs won’t be enough. Along with the NCERTs, you also need to refer to other advanced level books in order to prepare well for the exam.

Is there any provision for negative marking in the GPAT 2025 exam?

Yes, there is a provision for negative marking in the GPAT 2025 exam. For every correct answer, 4 marks will be awarded and for every incorrect answer, 1 mark will be deducted.

Can I appear for the GPAT 2025 exam in a language other than English?

No, it is clearly mentioned in the NBEMS's official notification that the GPAT 2025 exam will only be conducted in English language. 

How many questions will be there in the GPAT exam and what is the duration of the exam?

There will be a total of 125 questions in the GPAT exam and the total marks are 500. The duration of the GPAT exam is 3 hours, that is, 180 minutes.

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